TMA - 2019
Home: TMA - 2019 - Clinical Research and Product Development Fellowships
EDCTP-Clinical Research and Product Development Fellow: Dr Amadou Hamidou Togo, MD, PhD, Université des Sciences Techniques et Technologiques de Bamako(USTTB), Faculty of Pharmacy (FAPH), Malaria Research and Training Center (MRTC)
Grant Agreement number: TMA2019IF-2867
Grant Title: TMA2019 IF [ TOGO]
Call for proposals: TMA2019 IF [ TOGO]
The purpose of this Call for Proposals is to support researchers and members of clinical trial research teams from low- and middle-income countries (LMICs) through placements in product development organisations, including pharmaceutical companies and product development partnerships (PDPs).
2019 Mar - 2024 Feb | $11.4M
Assessing safety, efficacy and transmission blocking properties of the new anti-malarial KAF156 combined with a new formulation of lumefantrine in children and adults with uncomplicated Plasmodium sp. malaria in West and Central Africa (WANECAM II) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Abdoulaye Djimde | Gabon, Burkina Faso, Mali, Niger
2019 Oct - 2022 Oct | $703k
Using single-cell RNAseq to investigate human malaria parasite transmission dynamics Medical Research Council (MRC), UK, Wellcome Trust Sanger Institute, UK, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Mara K. N. Lawniczak, Abdoulaye Djimde | Africa, Central, Africa, Eastern, Africa, Southern, Mali, United Kingdom
2016 Feb - 2021 Jan | $7.87M
Developing Excellence in Leadership and Genetic Training for Malaria Elimination in Sub-Saharan Africa (DELGEME) Wellcome Trust, UK, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Abdoulaye Djimde | Africa, Central, Africa, Eastern, Africa, Southern, Africa, Western, Mali
2017 Jun - 2019 Dec | $314k
Evaluation of Seasonal Malaria Chemoprevention (SMC) pilot in Kita District, Mali U.S. President's Malaria Initiative (PMI), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Seydou Doumbia, Alassane Dicko | Mali
2014 Oct - 2019 Apr | $450k
Optimization of Seasonal Malaria Chemoprevention (SMC) delivery and its effects on the acquisition of malaria immunity National Institute of Allergy and Infectious Diseases (NIAID), NIH, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Alassane Dicko | Mali
2019 May - 2021 Apr
Development of an ex-vivo transmission blocking assay for clinical isolates of matured Plasmodium falciparum gametocytes through membrane feeding assays African Academy of Science (AAS), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Dinkorma Ouologuem | Africa, Central, Africa, Eastern, Africa, Southern, Mali
2017 Jun - 2019 May
Characterization of Plasmodium falciparum gametocytes infectiousness determinants in Mali University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Dinkorma Ouologuem | Africa, Central, Africa, Eastern, Africa, Southern, Mali
2019 Mar - 2024 Feb | $7.09M
Efficacy and Safety of a newly registered Artemisinin-Based Combination (Pyronaridine-Artesunate -PYRAMAX®) for the treatment of uncomplicated malaria in African pregnant women (PYRAPREG) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Dem. Rep. Congo, Mozambique, Burkina Faso, Gambia, Mali
2019 Mar - 2024 Feb | $7.09M
Efficacy and Safety of a newly registered Artemisinin-Based Combination (Pyronaridine-Artesunate -PYRAMAX®) for the treatment of uncomplicated malaria in African pregnant women (PYRAPREG) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Dem. Rep. Congo, Mozambique, Burkina Faso, Gambia, Mali
2021 Jan - 2024 Jan
Increasing the uptake of IPTp-SP through Seasonal Malaria Chemoprevention channel delivery (INTEGRATION study) R-Evolution Worldwide, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali, Research Institute of Health Sciences (IRSS), Burkina Faso | Kassoum Kayentao | Burkina Faso, Mali
2021 Jan - 2023 Dec
Increasing Intermittent Preventive Treatment uptake through enhanced antenatal clinic service delivery to improve maternal and child health & assessing ANC data for routine monitoring in Mali U.S. President's Malaria Initiative (PMI), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao, Celia Woodfill | Mali
2016 Dec - 2022 Dec | 1 subproject
Proactive Community Case Management and Child Survival: A Cluster-Randomized Controlled Trial Child Relief International Foundation, Grand Challenges Canada, Johnson & Johnson Foundation, United States Agency for International Development (USAID), University of California San Francisco (UCSF), USA, Malaria Research and Training Center (MRTC), University of Bamako, Mali | Kassoum Kayentao, Nancy S. Padian | Mali
2019 Mar - 2021 Mar | $400k
Increasing Intermittent Preventive Treatment uptake through enhanced antenatal clinic service delivery to improve maternal and child health U.S. President's Malaria Initiative (PMI), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Mali
2019 Jan - 2020 Dec
Ex-vivo clinical candidate drug assay against field clinical isolated blood stages parasites of P. malariae and P. ovale using 10 compounds from MMV. Medicines for Malaria Venture (MMV), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ghana, Mali
2018 Dec - 2020 Nov | $168k
Understanding the biology of Plasmodium vivax and Plasmodium ovale for the development of a field-based anti-hypnozoite drug screening model (HypnoBio) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ethiopia, Mali
2018 Jan - 2019 Dec
Establishment of an optimized in vitro screening platform for evaluation of antimalarial compounds against liver stages including hypnozoites of Plasmodium vivax and P. ovale using field isolated parasites Medicines for Malaria Venture (MMV), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ethiopia, Mali
2007 May - 2008 Jun
Randomized Controlled Trial to Evaluate the Safety and Immunogenicity of Recombinant Pichia Pastoris-Expressed P. Falciparum Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) Versus Tetanus Toxoid, in Healthy Malian Adult in Bandiagara African Malaria Network Trust (AMANET), Tanzania, University of Bamako, Mali | Mahamadou A. Thera | Africa, Western, Mali
2008 May - 2010 Dec
Immunogenicity, Efficacy and Safety Study of an MSP3-LSP (Long Synthetic Peptide) Malaria Vaccine African Malaria Network Trust (AMANET), Tanzania, University of Bamako, Mali | Mahamadou S. Sissoko | Africa, Western, Mali
2013 Oct - 2014 Apr
School-aged children based seasonal malaria chemoprevention using artesunate-amodiaquine in Mali National Center for Scientific and Technological Research (CNRST), Mali, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Ogobara Doumbo, Mahamadou S. Sissoko | Mali
2010 Dec - 2012 Jun | $653k
West Africa Malaria Initiative (WAMI) Spanish Agency for International Development Cooperation (AECID), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Ogobara Doumbo | Africa, Western
2019 Mar - 2023 Feb | $7.64M
Clinical evaluation of AntimalarialS tri-therapy with AtovAquone-Proguanil for treatment of uncomplicated malaria in African children (ASAAP) European & Developing Countries Clinical Trials Partnership (EDCTP), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana | Oumou Maiga-Ascofare | Gabon, Benin, Burkina Faso, Guinea, Mali
DELGEME
The Developing Excellence in Leadership and Genetics Training for Malaria Elimination in sub-Saharan Africa (DELGEME) is a training programme sponsored by the Wellcome Trust Developing Excellence in Leadership, Training and Science Africa (DELTAS Africa) initiative in partnership with the Department of International Development (DFID) and the Alliance for Accelerating Excellence in Science in Africa (AESA).
Please click on this to see www.delgeme.org
WANECAM
WANECAM is the West African Network for Clinical Trials of Antimalarial drugs. This network is being supported by grants from the European & Developing Countries Clinical Trials Partnership (EDCTP).
The WANECAM 2 project aims to accelerate the development of the Ganaplacide/lumefantrine combination for the treatment of uncomplicated malaria by conducting clinical trials in four countries in West and Central Africa: Burkina Faso, Gabon, Mali and Niger.
PYRAPREG
Malaria in pregnant is a public health problem in sub Saharan countries where 11 million pregnancies are exposed to malaria infection. Plasmodium falciparum in pregnant can cause adverse maternal health and poor birth outcomes. Artemisin-based Combination Therapy (ACT) used in treatment of uncomplicated Plasmodium falciparum malaria in pregnant women has the efficacy in Africa. The malaria parasite has shown resistance to Sulfadoxine-Pyrimethamin (SP) used in intermittent preventive treatment (IPTp). Other ACT as Dihydroartemisinin-Piperaquine (DP) is a potential candidate to replace SP in IPTp. Deployment of DP as IPTp would limit significantly its use as curative treatment. There is the need of other ACT to increase therapeutic options for malaria treatment in 2nd and 3rd trimester. Pyronaridine – Artesunate (PA) can be is a potential candidate.
PfTBV-Consortuim
Assessing safety, efficacy and transmission blocking properties of the new anti-malarial KAF156 combined with a new formulation of lumefantrine in children and adults with uncomplicated Plasmodium sp. malaria in West and Central Africa (WANECAM II) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Abdoulaye Djimde | Gabon, Burkina Faso, Mali, Niger
