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Dr Karim Traore
BMP Senior Scientist
Biosketch

Dr Karim Traore is a medical doctor with a PhD degree in biology, he is also a specialist in infectious diseases and anthropology. Dr Traore is a senior scientist of Bandiagara Malaria project at Malaria research and training center, faculty of medicine and dentistry of Mali. Since 2003, Dr Traore is involved in malaria clinical trials for vaccine and drug development, and epidemiological studies in both adult and children. The area of expertise of Dr Traore include epigenetics, interaction of environment and human genetic in susceptibility to infectious diseases. As senior researcher, Dr Traore is also involved in teaching parasitology and mycology, and ethics at the university of Sciences, Techniques, and Technologies of Bamako, and the training of MDs and master’s degree students. Dr Traore has been the coordinator of an ethic consortium involving Mali, Ghana, Guinea, and the catholic university of Lyon in France funded by EDCTP. Une image contenant personne, complet, homme, souriant Description générée automatiquement

Dr Traore earned his MD degree at the school of medicine and pharmacy of Mali in 2002, then successively completed a master’s degree in anthropo-biology, a diploma of specialization (DES) in infectious diseases at the university Cheick Anta Diop of Dakar in Senegal in 2011 and 2012, and a PhD degree at the university of Lyon, France in 2018. Since 2020 Dr Traore is an EDCTP senior fellow.


Actual work

The current work of Dr Traore include:

    Senior fellowship of EDCTP funded program on research capacity development (TMA2018SF-2471), 2020-24. Under this senior fellowship, Dr Traore is conducting a clinical trial to evaluate the safety and efficacy of dihydroartemisinine plus piperaquine compared to sulfadoxine pyrimethamine in malaria chemoprevention in school-aged children in Bandiagara. Senior fellowship also includes the training and mentoring of MD candidate, master and PhD students.
    Clinical coordinator of a phase 1a malaria vaccine trial testing a vaccine candidate derived from P. falciparum merozoite surface protein 3 associated with CRM manufactured by Vac-4-All from 2021 to present.
    Co-investigator of pediatric malaria incidence studies from 2021 to present.
    Clinical Monitor of clinical trials and epidemiological studies being conducted or coordinated by MRTC
    Teaching parasitology -mycology, and ethics

Selected publications

  1. Traore K, Konate S, Thera MA, Niangaly A, Ba A, Niare A, Di Cristofaro J, Baby M, Picot S, Chiaroni J, Boetsch G, Doumbo OK. (2019) Genetic polymorphisms with erythrocyte traits in malaria endemic areas of Mali. PLoS ONE.2019; 14(1): e0209966.
  2. Traore K, Thera MA, Bienvenu A-L, Arama C, Bonnot G, Lavoignat A, Doumbo OK, Picot S. Interaction between environment, nutrient-derived metabolites, and immunity: A possible role in malaria susceptibility/resistance in Fulani and Dogon of Mali. PLOS ONE. 2017;12(12):e0189724.
  3. Maiga H, Grivoyannis A, Sagara I, Traore K, Traore OB, Tolo Y, Traore A, Bamadio A, Traore ZI, Sanogo K, Doumbo OK, Plowe CV, Djimde AA. Selection of pfcrt K76 and pfmdr1 N86 Coding Alleles after Uncomplicated Malaria Treatment by Artemether-Lumefantrine in Mali. Int J Mol Sci. 2021 Jun 3;22(11):6057. doi: 10.3390/ijms22116057. PMID: 34205228; PMCID: PMC8200001.
  4. Thomson-Luque R, Votborg-Novél L, Ndovie W, et al. Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes. Nat Commun. 2021 Jul 30;12(1):4711. doi: 10.1038/s41467-021-25062-z. PMID: 34330920; PMCID: PMC8324851
  5. Traore K, Bull* S, Niare A, Konate S, Thera MA, Kwiatkowski D, et al. Understandings of genomic research in developing countries: a qualitative study of the views of MalariaGEN participants in Mali. BMC Med Ethics 2015; 16 (1):42.
  6. Traore K, Lavoignat A, Bonnot G, Sow F, Bess GC, Chavant M, et al. Drying anti-malarial drugs in vitro tests to outsource SYBR green assays. Malar J. 2015;14(1):90.

EDCTP Senior Fellow: Dr Karim Traore, MD, PhD